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. Author manuscript; available in PMC: 2006 Jun 1.
Published in final edited form as: Arch Ophthalmol. 2001 Oct;119(10):1439–1452. doi: 10.1001/archopht.119.10.1439

Figure 2.

Figure 2

Examples of lens opacity progression in Age-Related Eye Disease Study (AREDS) participants. Nuclear opacity graded from slitlamp photographs (model SL-6E; Topcon Corp, Tokyo, Japan) increased from 2.0 U (equal to AREDS standard photograph 3) at baseline (A) to 3.9 U (approaching standard photograph 5) at the 5-year visit (B). Cortical opacity within 5 mm of the lens center (ie, within the second innermost circle of the grid) graded from retroillumination photographs (Neitz Instruments Co, Ltd, Tokyo) increased from 6% at baseline (C) to 45% at the 6-year visit (D). Posterior subcapsular opacity within 5 mm of the lens center increased from 6% at baseline (E) to 22% at the 5-year visit (F).