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Effect of resveratrol (Res) on mRNA expression of PGC-1α (A), Nrf-1 (B), and Tfam (C) in CAECs. Knockdown of SIRT1 (siRNA) prevented resveratrol-induced upregulation of mitochondrial biogenesis factors. *P < 0.05 vs. control; #P < 0.05 vs. resveratrol only; n = 5 in each group.