Table 4.

Hot flashes and odds of aortic and coronary calcification

	Aortic calcification		Coronary calcification

	OR (CI)^*	p	OR (CI)^*	p
Model 1	1.55 (1.10–2.19)	0.01	1.48 (1.04–2.12)	0.03
Model 2	1.53 (1.02–2.29)^†	0.04	1.34 (0.88–2.05)^‡	0.17
Model 3	1.53 (1.02–2.29)^§	0.04	1.33 (0.87–2.03)^‖	0.19
Model 4	1.63 (1.07–2.49)	0.02	1.31 (0.84–2.05)	0.24

OR for any vs. no hot flashes

Model 1: Age, site, race

^†

Model 2a: Model 1 covariates plus BMI, smoking, education, SBP, LDL, HDL, triglycerides, glucose, physical activity, antidepressant use, depressive symptoms, HT use, lipid medication use, menopausal status

^‡

Model 2b: Model 1 covariates plus BMI, education, SBP, LDL, HDL, triglycerides, glucose, diabetes history, antidepressant use, depressive symptoms, HT use, menopausal status

^§

Model 3a: Model 2a covariates plus diabetes history

^‖

Model 3b: Model 2b covariates plus diabetes history, smoking, physical activity, lipid medication use

Model 4: Model 3 covariates plus E2_log, blood draw timing