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. Author manuscript; available in PMC: 2010 Jul 1.
Published in final edited form as: Biol Psychiatry. 2009 Apr 9;66(1):84–90. doi: 10.1016/j.biopsych.2009.02.007

Figure 1.

Figure 1

CUS produces significant effects on locomotor activity. (A) CUS produced a significant stress (F1,42 =4.83, p<0.05) and genotype effect (F1,42 =4.22, p<0.05) on locomotor activity in females. The female stressed BDNF KOs were significant hypoactivity compared to stressed CTLs and nonstressed BDNF KOs (*p<0.05). (B) CUS produced a significant stress effect (F1,30 =7.75, p<0.01) on locomotor activity in males. Male BDNF KO mice were hyperactive compared to CTL mice at baseline (*p<0.05). After CUS, male mice (*p<0.05) were significantly less active than their nonstressed cohorts while no significant effect was observed in nonstressed KOs compared to stressed KOs (p>0.05).