Table 1.
Clinical charecteristics of sample donors
| Lumbar Samples | Sample number (N) | Age (mean ± S.D) | Sex (M/F) | MMSE (mean, range) |
|---|---|---|---|---|
| Normal Control | 13 | 76.2 ± 7.34 | 6/7 | 29 (27–30)*** |
| AD | 13 | 74.3 ± 8.07 | 10/3 | 24 (17–28) |
| Postmortem samples | Sample number (N) | Age (mean ± S.D) | Sex (M/F) | postmortem interval (hours) |
| Normal Control | 5 Normal control | 72.3 ± 10.0 | 5 | 25.0 ± 10.4 |
| AD group | 10 AD | 83.7 ± 10.2 | 5/5 | 18.9 ± 10.4 |
| non-AD dementia group | 5 DLB, MSA, VAD | 78.4 ± 9.4 | 3/2 | 20.4 ± 8.8 |
Abreviations: AD: Alzheimer’s disease; DLB: dementia with Lewy bodies; MSA: multiple system atrophy; VAD: vascular dementia; MMSE: Mini Mental State Examination; M: Male; F: Female.
***
p=0.001, Normal control vs AD; no significant difference in age between nomal control and AD.
No significant difference in age and postmortem interval between three groups.