Table 3.

Table 3A. ESR1 - Single SNP analysis of association with PMDD
	PMDD (n=91)	Controls (n=56)	P values
SNP	MAF	MAF	Alleles	Genotypes
L0017	0.443	0.473	0.626	0.8659
L0018	0.411	0.429	0.769	0.7016
L0019	0.411	0.429	0.769	0.7016
L0020	0.017	0.036	0.316	1.000
L0024	0.094	0.063	0.326	0.5672
L0055	0.317	0.352	0.552	0.7712
L0058	0.200	0.295	0.070	0.1814
L0025	0.125	0.246	0.009	0.0169
L0060	0.279	0.434	0.008	0.0223
L0061	0.276	0.425	0.011	0.0357
L0057	0.136	0.226	0.057	0.1212
L0026	0.287	0.420	0.020	0.0437
L0056	0.324	0.380	0.339	0.5855
L0021	0.062	0.130	0.053	0.1203
L0023	0.285	0.348	0.261	0.4103
L0022	0.182	0.173	0.845	0.5149

Table 3B. SNPs in ESR2 are not associated with PMDD: pairwise anaylsis
	PMS (n=91)	Controls (n=56)	P values
SNP	Minor allele frequency	Minor allele frequency	Alleles	Genotypes
L0027	0.448	0.519	0.252	0.4627
L0028	0.138	0.098	0.338	0.442
L0030	0.461	0.391	0.241	0.493
L0031	0.476	0.422	0.382	0.245
L0032	0.135	0.147	0.779	0.224
L0034	0.074	0.127	0.138	0.283

note: p values were caculated using the χ² test.