Figure 3.
Sensitivity of lig4 mutant cells to DNA damaging agents. Cells were exposed to UV, MMS, or ionizing radiation as indicated. Survival data are shown from at least three independent experiments. Standard deviations are shown where relevant for judgment of differences between strains. Matching test and control strains were always assayed in parallel as detailed in Materials and Methods. The strains used are listed with genotypes in Table 2 and are referred to in the figure as (wt) FF18734 and FF18984 (▪); (lig4) PRSY003,1 and PRSY004,2 (□); (rad52) FF18743 (♦); (lig4 rad52) PRSY005, PRSY006 (⋄); (cdc9) PRSY009 (•); and (cdc9 lig4) PRSY011 (○).