Table 1.
Mating-type heterozygosity increases rDNA marker loss of the W303R haploid—deletion of fob1 suppresses the rDNA recombination defect of a sir2 hml mutant
| Strain
|
Rate of rDNA marker loss (× 103)
|
|---|---|
| W303R | 1.1 (0.1) |
| sir4 | 2.3 (0.1) |
| sir4 hml | 0.9 (0.3) |
| sir2 | 18.4 (4.6) |
| sir2 hml | 9.0 (0.6) |
| sir2 fob1 hml | 0.8 (0.1) |
Strain W303R carries a copy of ADE2 integrated into the rDNA (see Materials and Methods for a discussion of the half sector assay). Mean values for the rate of marker loss are given with standard deviation in parentheses. A total of least 20,000 colonies from three independent isolates were examined for each strain.