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Occludin. WW sequences are highly preserved 35-45 aminoacid segments, containing Trp and Pro. They recognize proline rich domains. Ser 379 and Thr 375 are casein kinase 2 (CK2) phosphorylation sites. PKC: Protein kinase C; PI3K: Phosphatidylinositol 3 kinase; PP2A: Protein phosphatase 2A; ZO: Zonula occludens.
