Table 2. Linear regression results of the association between the levels of sex hormonesa and the depressive symptoms (GDS)b.
| Unadjusted results | Adjustedc results | |||
|---|---|---|---|---|
| β (95% CI) | P | β (95% CI) | P | |
| Total testosterone (ng ml−1) | 0.020 (−0.093, 0.133) | 0.730 | −0.032 (−0.156, 0.091) | 0.607 |
| SHBG (nmol l−1) | −0.002 (−0.132, 0.127) | 0.974 | −0.068 (−0.215, 0.079) | 0.365 |
| Free androgen index | 0.027 (−0.099, 0.153) | 0.677 | 0.018 (−0.116, 0.152) | 0.788 |
| DHEA (ng ml−1) | −0.134 (−0.221, −0.047) | 0.003 | −0.110 (−0.199, −0.022) | 0.015 |
| DHEAS (mg ml−1) | −0.090 (−0.165, −0.015) | 0.018 | −0.074 (−0.149, 0.001) | 0.055 |
| DHEA/DHEAS ratio | −0.022 (−0.146, 0.101) | 0.721 | −0.015 (−0.137, 0.107) | 0.810 |
| Oestradiol (pg ml−1) | 0.096 (−0.036, 0.227) | 0.153 | 0.063 (−0.069, 0.196) | 0.346 |
| Free testosterone (ng dl−1) | 0.020 (−0.106, 0.146) | 0.758 | −0.021 (−0.155, 0.114) | 0.761 |
| Free oestradiol (pg ml−1) | 0.092 (−0.040, 0.225) | 0.173 | 0.081 (−0.055, 0.216) | 0.244 |
Abbreviations: BMI, body mass index; CHF, congestive heart failure; DHEA, dehydroepiandrosterone; DHEAS, dehydroepiandrosterone sulphate; GDS, Geriatric Depression Scale; MI, myocardial infarction; SHBG, sex hormone-binding globulin.
a
Sex hormone levels were log transformed.
b
The square root of the GDS was used.
c
Adjusted for age, education, BMI, smoking, MI/angina/CHF, diabetes and previous diagnosis of prostate cancer.