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Western blot analysis for GRP78, p-ERK and caspase-12, and quantification of corresponding protein levels. Animals were divided into four groups: the control group (N), the cisplatin (CP) group (C), the grape seed proanthocyanidin extract (GSPE) group (G) and the CP+GSPE group (C+G). Data are expressed as mean ± SD levels relative to β-actin. *Statistically significant difference compared to the N group (P<0.05); #statistically significant difference compared to the C group (P<0.05).
