Table 2.
Tertiles of aggression reactivity as a predictor of incident of hypomania in sample of patients with depression and/or anxiety disorder
| Lower scores | Intermediate scores | Higher scores | p Value for trend a | |
|---|---|---|---|---|
| Tertiles of aggression reactivity | ||||
| Participants, no. | 590 | 623 | 525 | |
| Cases, no. (%) | 4 (0.7%) | 6 (1.0%) | 18 (3.4%) | |
| Hazard ratio (95% confidence interval) | ||||
| Crude | 1.0 (ref) | 1.41 (0.40–4.99) | 5.27 (1.79–15.6) | <.001 |
| Adjustedb | 1.0 (ref) | 1.37 (0.39–4.88) | 4.87 (1.63–14.6) | <.001 |
| Fully adjusted modelc | 1.0 (ref) | 1.34 (0.37–4.69) | 4.63 (1.54–13.9) | .037 |
| Continuous aggression reactivity (z‐value) | ||||
| Hazard ratio (95% confidence interval) | ||||
| Crude | 1.84 (1.41–2.41) | <.001 | ||
| Adjustedb | 1.78 (1.36–2.35) | <.001 | ||
| Fully adjusted modelc | 1.4 (1.02–1.93) | .037 | ||
a
Data obtained by an analysis of variance for trend, linear term.
b
Adjusted for gender, age, level of education.
c
Additionally adjusted for alcohol dependence and severity of depression symptoms (IDS).